The response of tissues to combined hyperthermia and X rays

Abstract
Three normal tissues in mice and rats (skin, intestine and cartilage) were used to investigate the effects of combined hyperthermia and radiation. The heating time was kept constant at 1 h and X-rays were given either immediately before or after heating. Thermal enhancement ratios were measured as a function of temperature up to 43.degree. C and were compared with data for other normal tissues and tumors taken from the literature. The variation from tissue to tissue was fairly small within this temperature range, but there is some indication of a greater response of tumors.