Therapeutic, Toxic, and Lethal Concentrations in Human Fluids of 90 Drugs Affecting the Cardiovascular and Hematopoietic Systems
- 1 January 1997
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology: Clinical Toxicology
- Vol. 35 (4) , 345-351
- https://doi.org/10.3109/15563659709043365
Abstract
Background: Drugs affecting the cardiovascular and hematopoietic systems are frequently involved in poisoning. As a continuation of our previously published study about the concentrations of drugs of abuse, we have compiled published data about these drugs and subjected them to selection and unification on the basis of conservative criteria and our own experience. Results: A compilation of the concentrations of 90 drugs affecting heart, circulation, blood or hematopoietic organs, in whole blood, serum/plasma, and urine, corresponding to therapeutic, toxic or lethal concentrations is given. Although the interpretation of the concentration is a complex and difficult problem, the presented table can be helpful in interpretation from the actual concentrations of this group of drugs encountered in clinical, toxicological and forensic casesKeywords
This publication has 7 references indexed in Scilit:
- Habitual, Toxic, and Lethal, and Lethal Concentration of 103 Drugs of Abuse in HumansJournal of Toxicology: Clinical Toxicology, 1997
- Zusammenstellung therapeutischer und toxischer Plasmakonzentrationsbereiche von ArzneistoffenDer Anaesthesist, 1994
- Post-mortem drug redistribution — A toxicological nightmareForensic Science International, 1990
- The Forensic Science Implications of Site and Temporal Influences on Postmortem Blood-Drug ConcentrationsJournal of Forensic Sciences, 1990
- A Collection of Therapeutic, Toxic and Fatal Blood Drug Concentrations in ManHuman Toxicology, 1983