Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica
- 1 August 1982
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 22 (2) , 342-345
- https://doi.org/10.1128/aac.22.2.342
Abstract
Bruceantin, purified from an Ethiopian plant used to treat dysentery, killed Entamoeba histolytica in vitro (IC50 [the concentration of drug which decreased the number of colonies to half that of controls] = 0.018 microgram/ml). Six related quassinoids of 17 tested were also amoebicidal. No relationship between quassinoid structure and amoebicidal activity was apparent.This publication has 9 references indexed in Scilit:
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