Ten-Year Longitudinal Study of Children at High Risk of Insulin-Dependent Diabetes Mellitus
- 19 November 1987
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (21) , 1352-1353
- https://doi.org/10.1056/nejm198711193172114
Abstract
To the Editor: The frequency of Type 1 diabetes, or insulin-dependent diabetes mellitus (IDDM), in the general population is about 1 in 600.1 In contrast, in families in which one child has IDDM, the likelihood that another child will have IDDM is about 100 times higher.2 This latter high-risk population seemed an ideal group in which to identify some of the factors that might precede the development of clinically apparent IDDM.In 1977 we initiated a long-term longitudinal study of families in which one child had IDDM.3 , 4 When a proband was identified and the family was entered in the study, . . .Keywords
This publication has 6 references indexed in Scilit:
- Multiple immunological abnormalities in patients with Type 1 (insulin-dependent) diabetes mellitusDiabetologia, 1987
- First-Degree Relatives of Patients with Type I Diabetes MellitusNew England Journal of Medicine, 1985
- Can future type I diabetes be predicted? A study in families of affected childrenDiabetes, 1982
- HLA antigens, cytoplasmic islet cell antibodies, and carbohydrate tolerance in families of children with insulin-dependent diabetes mellitusDiabetes, 1982
- The Pittsburgh study of insulin-dependent diabetes mellitus. Risk for diabetes among relatives of IDDMDiabetes, 1982
- Prevalence of diabetes mellitus in school-age children in MinnesotaDiabetes, 1978