Antiallergic activity of some 9H-xanthen-9-one-2-carboxylic acids
- 1 December 1978
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 21 (12) , 1327-1330
- https://doi.org/10.1021/jm00210a034
Abstract
The synthesis and antiallergic activity of a new series of 9H-xanthen-9-one-2-carboxylic acids are described. Antiallergic activity was evaluated in the rat passive cutaneous anaphylaxis (PCA) screen. Biological results were analyzed using regression analysis techniques, and the antiallergic activity of the compounds in the series was found to be highly correlated with substituent size.This publication has 1 reference indexed in Scilit:
- Quantitative Models of Steric EffectsPublished by Wiley ,1976