Chiari's Disease — Hepatic-Vein Thrombosis

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Abstract
HEPATIC-VEIN thrombosis was first described by Budd1 in 1846 but is named for Chiari, 2 who in 1899 collected 10 cases. Since then over a hundred additional cases have been reported. The Budd-Chiari syndrome, or hepatic-vein thrombosis, may be divided into two major groups: those due to a primary endophlebitic process and others secondary to intrahepatic and extrahepatic disorders. Less than 12 reported cases have been of the primary endophlebitic type. Hirsh3 has listed many of the causative diseases leading to the secondary type, including those of thrombotic, infectious and neo-plastic etiology.The theoretical considerations of abnormalities of clot formation are . . .

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