The gene encoding myeloid α-3-fucosyltransferase (FUT4) is located between D11S388 and D11S919 on 11q21
- 1 January 1994
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 66 (2) , 104-106
- https://doi.org/10.1159/000133677
Abstract
The last step in the biosynthesis of Lex antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different α-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid α-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.Keywords
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