The effect of consecutive cycles of clomiphene citrate therapy on endometrial thickness and echo pattern
- 30 September 1995
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Obstetrics & Gynecology
- Vol. 86 (3) , 341-345
- https://doi.org/10.1016/0029-7844(95)00165-n
Abstract
Conclusion: One proposed mechanism for the dichotomy between ovulation and pregnancy rates after clomiphene citrate therapy is that the drug adversely affects the endometrium. If clomiphene citrate does affect implantation adversely, the mechanism does not seem to be related to thinning the endometrium or causing an echo pattern that indicates a poor prognosis. The data also suggest that estrogen supplementation does not influence endometrial thickness and would best be used exclusively for hostile cervical mucus.Keywords
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