MECHANISM OF DEVELOPMENT AND MORPHOLOGY OF SECONDARY CARCINOMAS OF OVIDUCTS IN PRIMARY UTERINE CORPUS CARCINOMA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 23  (5) , 549-557
Abstract
The incidence and morphology of metastases in 284 fallopian tubes from 148 patients with primary uterine corpus cancer were investigated. In 44 patients metastases were discovered in inner organs, 17 of which (11.5% patients) were in 23 oviducts. In 10 of these patients the fallopian tubes were the only localization of metastases. Macroscopic alterations in the form of thickening condensation and tumor nodules on the surface of the affected oviducts were discovered in 7 cases. In the remainder no macroscopic changes were noted. Lymphogenic metastases predominated. In a smaller number of cases there were implantation and lymphogenoimplantation metastases, localized mostly in the ampullary regions of the oviducts. More often, one could observe involvement by lymphogenic metastases of the subserosal layers together with muscular tissue, less frequently mucosal layers and total involvement of all layers of the wall of fallopian tubes in the form of single or multicentric tumor nests or diffuse tumor infiltration of tissues of the oviduct wall. Implantation metastases in the form of micronodules and multicellular agglomerates were discovered on the serosa more often than the mucosa of fallopian tubes. Secondary oviduct carcinomas differed from primary tumors by their histological structure and character of growth. The fallopian tubes play an essential role in the dissemination of metastases in the presence of primary uterine corpus carcinoma.

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