KAPOSIS SARCOMA AND MALIGNANT-LYMPHOMA - DISCUSSION OF THIS ASSOCIATION

  • 1 January 1977
    • journal article
    • research article
    • Vol. 104  (12) , 817-823
Abstract
Kaposi''s sarcoma was diagnosed in a 62 yr old female at the last stage of an indefined malignant lymphoma. Clinically and histopathologically, some cutaneous aspects were consistent with mycosis fungoides. The histological examination of lymph nodes led to the diagnosis of Hodgkin''s disease, sometimes associated with features of Kaposi''s sarcoma. During the past few years, the occurrence of Kaposi''s sarcoma in the course of cancers, malignant lymphomas and especially during Hodgkin''s disease, was reported. Immunosuppressive therapy undertaken for the initial tumor could account for viral carcinogenesis. In this respect, the vascular proliferation observed in Kaposi''s sarcoma could be compared with lymphocyte induced angiogenesis, which occurs during the experimental graft vs. host reaction. Kaposi''s sarcoma could be the result of tumor rejection. It does not seem possible to diagnose angioimmunoblastic lymphadenopathy; but it is of interest to note that, in this later disease, histological features of vascular neogenesis were also reported.

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