The fractionation of urinary iodine. 1. Method of analysis

Publisher Website
Google Scholar
Abstract
A method for the quantitative estimation of small amounts of I131-labeled thyroxine and di-iodotyrosine in the presence of large amounts of (I131) iodide in urine is presented. Iodide is removed as insoluble silver iodide by the use of a column of silver chloride. Under certain conditions thyroxine and di-iodotyrosine are not removed from the urine by the column. Thyroxine and di-iodotyrosine are concentrated from the urine by adsorption on an ion-exchange resin. The eluate from the resin, after extraction into butanol, is suitable for paper chromatography.