CUG codons inCandida spp.
- 1 February 1996
- journal article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 42 (2) , 321-322
- https://doi.org/10.1007/bf02198859
Abstract
Codon CUG is used for serine instead of for leucine, its usual assignment, in several yeasts of the genusCandida. We propose a series of steps for the reassignment, including disappearance of leucine CUG and its anticodon CAG, formation of a new serine tRNA, with anticodon CAG, from a duplication of the gene for serine tRNA (IGA), and then production of CUG codons by mutation at sites that are mostly “nonessential.”Keywords
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