Bee Venom Enhances Guanylate Cyclase Activity
- 17 July 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4505) , 359-360
- https://doi.org/10.1126/science.6113689
Abstract
Bee venom and phospholipase A2 extracted from bee venom enhanced guanylate cyclase (E.C. 4.6.1.2) activity two- to threefold in rat liver, lung, heart, kidney, ileum, and cerebellum. Dose-response relationships revealed that bee venom at concentrations as low as 1 microgram per milliliter and phospholipase A2 at 1 microunit per milliliter caused a maximal enhancement of guanylate cyclase.This publication has 14 references indexed in Scilit:
- Monooxygenase reactions glucuronic acid and sulphate conjugation in isolated hepatocytesToxicology, 1980
- Testosterone and its precursors and metabolites enhance guanylate cyclase activity.Proceedings of the National Academy of Sciences, 1979
- Activation of microsomal guanylate cyclase by a cytotoxic polypeptide: MelittinBiochemical and Biophysical Research Communications, 1979
- Activation of high levels of endogenous phospholipase A2 in cultured cells.Proceedings of the National Academy of Sciences, 1979
- Stimulation of guanylate cyclase activity by several fatty acidsBiochemical and Biophysical Research Communications, 1976
- Action of phospholipases on the cytoplasmic membrane of Escherichia coli. Stimulation by melittinBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- Cyclic nucleotide levels in incubations of guinea pig tracheaBiochimica et Biophysica Acta (BBA) - General Subjects, 1974
- Effects of Bradykinin and Indomethacin on Cyclic GMP and Cyclic AMP in Lung SlicesProceedings of the National Academy of Sciences, 1973
- Bee and Wasp VenomsScience, 1972
- Insect venoms: Identification of dopamine and noradrenaline in wasp and bee stingsCellular and Molecular Life Sciences, 1971