Follow-Up of Drug Therapy Efficacy to Prevent Recurrence of Calcium Oxalate Kidney Stone Formation

Abstract
Results of a prospective study of response to phosphate treatment after surgery in a group of kidney stone formers, some of them recurrent are presented. The follow-up, of 1 yr duration, was carried out by periodic tests of the stone formers'' urine using the discriminating index (DI) procedure. In a group of 32 stone formers, 30 individuals showed a remarkable change in the DI value; i.e., the inhibiting potential of their urine was similar to that of normals. Two the patients did not respond well, and their drug treatment was adjusted accordingly. During 1 yr, no recurrence was reported.