Intravenous Albumin in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

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Abstract
Patients in whom sepsis develops, particularly those who also have cirrhosis, are prone to the development of renal failure secondary to peripheral vasodilatation and subsequent renal arterial vasoconstriction. Sort et al. (Aug. 5 issue)1 reported on the effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. They found that in such patients, inadequate fluid resuscitation may result in further deterioration in renal function. This is not a new concept in medicine.