Complex de novo rearrangement involving four chromosomes and ten break points with interstitial deletions and duplication

Abstract
We describe an unusual de novo case of two interstitial deletions (5q22→5q31; 9p13→9q22) and one duplication (9q22→9q34) resulting from a 10–breakpoint, complex chromosome rearrangement of chromosomes 1, 5, 8, and 9 in a profoundly retarded woman.