MECHANISM INVOLVED IN THE METABOLISM OF NITROPHENYL-CARBOXYLIC ACID COMPOUNDS BY MICROORGANISMS

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Abstract
The dissimilation of ortho-nitrobenzoic acid (OBA) by a bacterium of the genus Flavobacterium was studied. This organism, capable of utilizing OBA for both its C and N requirements, was isolated from soil by enrichment procedure. Stanier''s method of simultaneous adaption was the principle method of investigation. These studies indicate that ortho-nitrosobenzoic acid and ortho-hydroxylamine benzoic acid are intermediary metabolities in the formation of cell protein from OBA. Additional studies also indicate that anthranilic acid, salicylic acid, protocatechuic acid, benzoic acid, catechol, ortho-nitrobenzyl alcohol, and ortho-nitrosophenol are not intermediates in the metabolism of OBA by this organism.