TWIN PAIRS, SMOKING IN PREGNANCY AND PERINATAL MORTALITY

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Abstract
Twins born in the province of Quebec during the first six months of 1972 were ascertained by reviewing all live births and perinatal death certificates. A total of 852 twins, constituting 426 pairs, were included in the study. Smoking habits of the mother during pregnancy were recorded at the hospital of birth for 88.5% of the pairs. The risk of at least one perinatal death was significantly higher for twin pairs born to smoking mothers. The Mantel-Haenszel test statistic controlling for sex of pairs, parity (0, 1 +), maternal age (p = 0.04). The standardized risk ratio for smoking versus nonsmoking mothers that a pair will have at least one death was 1.77 (95% confidence limits: 1.03–3.04). As expected, the relative risk of perinatal death associated with smoking appears to be higher for twins than for singletons.

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