THE EXCRETION OF HIPPURIC ACID IN SUBJECTS WITH FREE ANXIETY

Abstract
Free and bound anxiety are defined carefully and a clinical vignette of each group given. Individuals with free anxiety excrete more hippuric acid after the injn. of Na benzoate than other neurotics, psychotics or normal controls. This significant increase in hippuric acid excretion is not due to an elevated endogenous hippuric acid production in the free anxiety group. The hippuric acid excretion of the free anxiety group is reduced toward normal levels after psychotherapy which results in a diminution in free anxiety. Normal controls show no significant change in hippuric acid excretion over equivalent time intervals.

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