Structures of the Human Pyruvate Dehydrogenase Complex Cores: A Highly Conserved Catalytic Center with Flexible N-Terminal Domains
Open Access
- 1 January 2008
- Vol. 16 (1) , 104-114
- https://doi.org/10.1016/j.str.2007.10.024
Abstract
No abstract availableKeywords
This publication has 54 references indexed in Scilit:
- Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and RadicicolStructure, 2007
- A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain α-ketoacid dehydrogenase complexThe EMBO Journal, 2006
- Refinement of Protein Structures by Iterative Comparative Modeling and CryoEM Density FittingJournal of Molecular Biology, 2006
- Seeing GroEL at 6 Å Resolution by Single Particle Electron CryomicroscopyStructure, 2004
- UCSF Chimera—A visualization system for exploratory research and analysisJournal of Computational Chemistry, 2004
- Direct Evidence for the Size and Conformational Variability of the Pyruvate Dehydrogenase Complex Revealed by Three-dimensional Electron MicroscopyPublished by Elsevier ,2001
- EMAN: Semiautomated Software for High-Resolution Single-Particle ReconstructionsJournal of Structural Biology, 1999
- Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopyNature, 1997
- SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modelingElectrophoresis, 1997
- The High-resolution Structure of the Peripheral Subunit-binding Domain of Dihydrolipoamide Acetyltransferase from the Pyruvate Dehydrogenase Multienzyme Complex of Bacillus stearothermophilusJournal of Molecular Biology, 1993