Synthesis of 3-alkylpyridines. Part I: Total Synthesis of (±)-ikimine A
- 1 June 1994
- journal article
- research article
- Published by Taylor & Francis in Natural Product Letters
- Vol. 4 (3) , 223-226
- https://doi.org/10.1080/10575639408043909
Abstract
The cytostatic ikimine A (9) is prepared by a convergent synthesis based on acylation of 2-methyl-3-(2-thiophene)-1-propylacetate (2), reductive de- sulfurization, and functional group transformation as a general route to methyl branched racemic and nonracemic chiral 3-alkylpyridines.Keywords
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