Turbinamide, a New Selective Cytotoxic Agent from the Mediterranean Tunicate Sidnyum turbinatum

Abstract
A unique cytotoxic metabolite, turbinamide (1), has been isolated from the marine tunicate Sidnyumturbinatum through a bioassay-guided approach. Its structure has been elucidated by an extensive spectroscopic analysis. Turbinamide demonstrated a strong and selective cytotoxic effect against neuronal cells rather than immune system cells.