Synthetic access to α-substituted prop-2-ynylamines and α-acetylenic amino acids via the t-butyl N-trimethylsilylprop-2-ynylcarbamate dianion

1 January 1979

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 3,p. 119-120
https://doi.org/10.1039/c39790000119

Abstract

The dianion derived from t-butyl N-trimethyl-silylprop-2-ynycarbamate undergoes alkylation and carboxylation at the propynylic position, leading to derivatives of acetylenic amines and amino acids.

Keywords

AMINO ACID