TheDrosophilaCdc6/18 protein has functions in both early and late S phase in S2 cells
Open Access
- 1 June 2005
- journal article
- Published by The Company of Biologists in Journal of Cell Science
- Vol. 118 (11) , 2451-2459
- https://doi.org/10.1242/jcs.02361
Abstract
The Cdc6/18 protein has been mainly characterised for its role in the initiation of DNA replication. Several studies exist, however, which suggest that it may also have a role in controlling the G2/M transition. Here we present studies on the Drosophila Cdc6 (DmCdc6) protein that support this dual function for the protein.Keywords
This publication has 29 references indexed in Scilit:
- Coordination of replication and transcription along a Drosophila chromosomeGenes & Development, 2004
- The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activationThe Journal of cell biology, 2004
- Cdc6 Chromatin Affinity Is Unaffected by Serine-54 Phosphorylation, S-Phase Progression, and Overexpression of Cyclin AMolecular and Cellular Biology, 2004
- Enigmatic VariationsMolecular Cell, 2003
- Dissecting mitosis by RNAi inDrosophila tissue culture cellsBiological Procedures Online, 2003
- DNA Replication in Eukaryotic CellsAnnual Review of Biochemistry, 2002
- Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1pNature Cell Biology, 2002
- Control of DNA Replication and Chromosome Ploidy by Geminin and Cyclin AMolecular and Cellular Biology, 2002
- Loss of Cell Cycle Checkpoint Control in Drosophila Rfc4 MutantsMolecular and Cellular Biology, 2001
- The fission yeast cdc18+ gene product couples S phase to START and mitosisCell, 1993