PLASMAPHERESIS WITH RETURN OF CRYOGLOBULIN-DEPLETED AUTOLOGOUS PLASMA (CRYOGLOBULINPHERESIS) IN CRYOGLOBULINEMIA

  • 1 January 1980
    • journal article
    • research article
    • Vol. 55  (5) , 866-870
Abstract
Three patients with cryoglobulinemia were treated with automated plasma exchange procedures in which the replacement fluid was autologous plasma, obtained at a previous plasmapheresis and incubated in the cold to precipitate abnormal protein. All 3 responded with a reduction in cryoglobulin level and an improvement in clinical manifestations of cryoglobulinemia. Treatment cost was less than that of conventional plasmapheresis, even though the quality of the replacement fluid was superior. The term cryoglobulinpheresis was suggested for this treatment process.