Regulation of Pyruvate Dehydrogenase in Heart Mitochondria

Abstract
The proportions of active (dephosphorylated) and inactive (phosphorylated) forms of pyruvate dehydrogenase and the adenine nucleotide and NAD levels were determined in rat heart mitochondria under various metabolic and energetic conditions. Both the ATP/ADP and the NADH/NAD.sym.-dehydrogenase interconversion.