In Vitro Metabolism of T-2 Toxin
- 1 January 1974
- journal article
- research article
- Published by American Society for Microbiology in Applied Microbiology
- Vol. 27 (2) , 423-424
- https://doi.org/10.1128/aem.27.2.423-424.1974
Abstract
Incubation of T-2 toxin with the 9,000 × g supernatant fluid of both human and bovine liver homogenate resulted in conversion to a single, deacetylated product identified as HT-2 toxin. Metabolism is more rapid in human liver. HT-2 toxin was not produced when human plasma was the incubating medium nor was it produced by treatment of T-2 toxin with simulated gastric juice. T-2 toxin was stable in gastric juice for at least 1 h.Keywords
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