Chronic Epilepsy in the Monkey Following Multiple Intracerebral Injections of Alumina Cream
- 1 October 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 78 (1) , 53-54
- https://doi.org/10.3181/00379727-78-18970
Abstract
1. Chronic experimental epilepsy was induced in 4 of 5 monkeys (Macaca mulatto) by multiple intracerebral injections of alumina cream in the sensori-motor area of one cerebral hemisphere. 2. The early motor convulsive manifestations in the epileptic animals resembled those described in man as epilepsia partialis continua (Koshewnikow). 3. In an additional monkey treated by multiple intracerebral injections of alumina cream into both hemispheres death in status epilepticus occurred 3 weeks after the onset of seizures. 4. EEG's showed marked spike, sharp, and slow wave activity which was most prominent over the injected hemisphere.Keywords
This publication has 1 reference indexed in Scilit:
- The epileptogenic effect of subcortical alumina cream in the rhesus monkeyElectroencephalography and Clinical Neurophysiology, 1950