General methods of alkaloid synthesis. A new approach to the synthesis of the 5,10b-ethanophenanthridine Amaryllidaceae alkaloids. The total synthesis of (±)-3-epi-elwesine

1 January 1970

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications

No. 23,p. 1585-1586
https://doi.org/10.1039/c29700001585

Abstract

Methyl vinyl ketone annelation of the Δ²- pyrroline (5b) prepared by acid-catalysed thermal rearrangement of the cyclopropyl imine (7) has been exploited in an efficient eight-step stereoselective total synthesis of racemic 3-epi-elwesine (3b).

Keywords

TOTAL SYNTHESIS