Differential Diagnosis, Investigation, and Current Treatment of Lower Limb Lymphedema

Abstract
LYMPHEDEMA IS the swelling of a body part due to an abnormality in the locoregional lymphatic drainage. This results in an increase in interstitial volume secondary to the accumulation of tissue (lymphatic) fluid. It is most common in the lower limb (80% of cases) but can also occur in the arms, face, trunk, and external genitalia.1