SUBJECTIVE ESTIMATION OF DRUG‐INDUCED CHANGES IN ACTIVATION LEVEL

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Abstract
For comparative evaluation of the subjective effects of 50 mg chlorpromazine, 0.10 g amobarbital and 10 mg amphetamine (phenopromine. sulf.) two types of formalized rating procedures—a verbal check list and graphic rating scales—were administered to 187 university students. Repeated self‐ratings were performed 45, 90 and 180 minutes after oral intake. By the check‐list method the expected difference between amphetamine and chlorpromazine was significantly established in all the three ratings. Only in the 45‐minute rating was a significant difference obtained between amobarbital and amphetamine. The graphic rating scales were clearly less efficient as judged from the greater proportion reporting ‘no change’.

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