Bacterial Meningitis — A Review of Selected Aspects

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Abstract
NOWHERE have the effects of the introduction of antimicrobial agents during the past two decades been more dramatically exhibited than in bacterial meningitis. Whereas formerly untreated pyogenic meningitis was fatal with rare exceptions,1 in the antibiotic era there has been a gratifying lowering of the mortality rate.2 3 4 5 But during the past eight to ten years, there has been no outstanding change in the mortality rate in the principal types of bacterial meningitis. Although it might appear that a plateau has been reached in the treatment of this disease, we are unwilling to accept this view without exploring fully the basis . . .

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