Succinylcholine and Muscle Excitability

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Abstract
Succinylcholine lowers the resting membrane potential taken with microelectrodes similarly in nerve-scarce and innervated portions of frog sartorius muscle. Twitches to electrical excitation of the nerve-scarce pelvic end of the muscle are also rapidly reduced. The results indicate that succinylcholine probably acts generally on the muscle membrane to diminish excitability.