A new genetic variant of Chlamydia trachomatis
Open Access
- 2 May 2007
- journal article
- editorial
- Published by BMJ in Sexually Transmitted Infections
- Vol. 83 (4) , 253-254
- https://doi.org/10.1136/sti.2007.026260
Abstract
A new variant of Chlamydia trachomatis was discovered in Sweden in 2006. This variant contains a mutant sequence that cannot be detected with either the Abbott m2000 (Abbott Diagnostics, Chicago, IL, USA) or Cobas Amplicor/TaqMan48 (Roche Diagnostics, Basel, Switzerland) systems.1 The first description reported that the new variant constituted 13% of all detected chlamydia infections (from mid-September to October 2006) in the county of Halland (south west of Sweden). It soon became apparent that the proportion was higher and that the new variant had spread widely in Sweden.2–4 We now know that in the counties that have used the Abbott or Roche test systems during the past year or so the new variant accounts for 20% to 65% of all detected chlamydia cases. In local areas, as many as 78% of all cases have been found to have the mutation (Britta Loré, personal communication).Keywords
This publication has 10 references indexed in Scilit:
- A Chlamydia trachomatis Strain With a 377-bp Deletion in the Cryptic Plasmid Causing False-Negative Nucleic Acid Amplification TestsSexually Transmitted Diseases, 2007
- High-Resolution Genotyping of Chlamydia trachomatis Strains by Multilocus Sequence AnalysisJournal of Clinical Microbiology, 2007
- Experiences with the new genetic variant of Chlamydia trachomatis in Örebro county, Sweden – proportion, characteristics and effective diagnostic solution in an emergent situationEurosurveillance, 2007
- Identification of the Swedish Chlamydia trachomatis variant among patients attending a STI clinic in Oslo, NorwayEurosurveillance, 2007
- Europe-wide investigation to assess the presence of new variant of Chlamydia trachomatis in Europe.2007
- No indication of Swedish Chlamydia trachomatis variant among STI clinic visitors in AmsterdamEurosurveillance, 2007
- Investigation to determine if newly-discovered variant of Chlamydia trachomatis is present in IrelandEurosurveillance, 2007
- Impact of a genetic variant of Chlamydia trachomatis on national detection rates in SwedenEurosurveillance, 2006
- A variant of Chlamydia trachomatis with deletion in cryptic plasmid: implications for use of PCR diagnostic testsEurosurveillance, 2006
- The 7.5-kb plasmid present in Chlamydia trachomatis is not essential for the growth of this microorganismPlasmid, 1990