Cleavage Analysis of Actinophage R4 and Its Deletion Mutants

Abstract
We have constructed restriction maps of actinophage R4 for PstI, PvuII, EcoRI, SeaI, KpnI, BglII and BclI. DNA of R4 phage had no cleavage sites for seven restriction endonucleases, BamHI, ClaI, HindIII, SacII, SlaI (XhoI) or XbaI. The entire genome size of the R4 phage was estimated to be 53.7 kilobases. Three deletions of the R4 phage were delimitated on the R4 genome. All three deletions were located on the right hand side of the R4 restriction map.

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