EFFECT OF GASTRIC DISTENSION ON SECRETION OF ACID AND PEPSIN BY PATIENTS WITH DUODENAL-ULCER

  • 1 January 1977
    • journal article
    • research article
    • Vol. 24  (4) , 271-277
Abstract
Patients (24) with active duodenal ulceration were subjected to gastric distension with a balloon, in an attempt to assess the neural tone affecting the parietal and chief cells of the stomach. Distension stimulated gastric secretion in a manner similar to, but weaker than, pentagastrin. No evidence was found that distension provides a specific neural stimulus to the gastric secretion of acid or pepsin in man.