Faculty Opinions recommendation of Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials.

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Abstract
This is the first paper that demonstrates an increased risk of serious infections and malignancies in patients treated with anti-TNF antibody therapy for rheumatoid arthritis using data from randomized controlled clinical trials. Physicians should discuss the potential risks of infections and malignancies with patients when deciding to use these agents. Serious infections and cancer are statistically rare; therefore, clinical trials...

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