Effect of Experimental Renal Hypertension on Experimental Thiouracil-Cholesterol Atherosclerosis in Dogs
- 1 July 1957
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 5 (4) , 426-434
- https://doi.org/10.1161/01.res.5.4.426
Abstract
Experimental renal hypertension accelerated the onset and accentuated the severity of thiouracil-cholesterol atherosclerosis in dogs. Increased blood pressure and other hemodynamic changes appear to be responsible for these effects. Hypertension and sex were without significant effect on serum cholesterol, cholesterol: phospholipid ratio and low density lipoproteins. Sex had no significant effect on the incidence or severity of this experimental atherosclerosis, including coronary involvement.Keywords
This publication has 5 references indexed in Scilit:
- Pathogenesis of Spontaneous and Pyelonephritic Hypertension in the DogCirculation Research, 1957
- Inhibition of Cholesterol-Induced Coronary Atherogenesis in the Egg-Producing HenCirculation, 1954
- Development of Atherosclerosis in Dogs with Hypercholesterolemia and Chronic HypertensionCirculation Research, 1954
- TREATMENT AND PROPHYLAXIS OF EXPERIMENTAL RENAL HYPERTENSION WITH RENIN1953
- Production of arteriosclerosis in dogs by cholesterol and thiouracil feedingAmerican Heart Journal, 1949