Nuclear pore complexes. Elimination and reconstruction during mitosis.
Open Access
- 1 August 1977
- journal article
- research article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 74 (2) , 492-500
- https://doi.org/10.1083/jcb.74.2.492
Abstract
Nuclear structures similar to those of the nuclear pore complex were found on chromosomes [of human melanoma LeCa cells]. Part of the pore complex was retained by the chromosomes through mitosis in the absence of the nuclear membrane. The formation of approximately the same number of pore complexes in the presence and absence of protein synthesis during the 1st 4 h after mitosis proved the reassembly rather than new synthesis of the pore complex. The structure of pore complexes reconstructed in the absence of protein synthesis cannot be distinguished from the structure of those of control cells.This publication has 23 references indexed in Scilit:
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