Contributions of Edward Jenner to Modern Concepts of Heart Disease

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Abstract
Jenner''s first postmortem on a case of angina pectoris was performed about 1772; he stated that the coronary arteries "were become bony canals." In another case "the coats of the arteries were hard and a sort of cartilagenous canal was formed within the cavity of each artery." Jenner ascribed the disease to the changes in the coronary arteries but did not pursue his studies because he feared the effect on his friend John Hunter who suffered from this malady. About 1778, Jenner with other friends formed a small society "to promote medical science, conviviality and good fellowship." To this society he presented a paper on angina pectoris; this paper later formed the basis of a book by Parry on the subject. Jenner was also among the first to note the relationship between rheumatic fever and heart disease, records of the society indicating that he presented a paper on this subject illustrated by dissections on July 29, 1789. Unfortunately neither of these papers was published at the time, and we have only statements of others and letters to support the claim for Jenner''s priority.

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