HEMOCHROMATOSIS
Open Access
- 1 April 1921
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 27 (4) , 406-420
- https://doi.org/10.1001/archinte.1921.00100100022002
Abstract
Hemochromatosis is a chronic disease of males occurring during middle life. Abbott1has reported one authentic case in a woman. It is characterized by (1) a pigmentation of the skin that varies from yellow to ashen gray and involves by preference the exposed parts, the axillae, and the genitals; (2) cirrhosis of the liver with moderate enlargement; (3) slight enlargement of the spleen; (4) fibrosis of the pancreas and lymph nodes; (5) hyperglycemia with or without glycosuria. It is not a common disease. There are records of but four cases of genuine hemochromatosis among 5,000 recent necropsies in Bellevue Hospital. Fuchter2found only three instances of this disease in the clinical records of the Johns Hopkins Hospital, covering 106,000 admissions. Clinically, hemochromatosis may easily be confused with other diseases attended by pigmentation of the skin. The pigment may not be visible. It may be late in its occurrence. It isThis publication has 3 references indexed in Scilit:
- METABOLISM IN A CASE OF HEMOCHROMATOSISArchives of internal medicine (1960), 1918
- THE OCCURRENCE OF FAT IN THE ISLANDS OF LANGERHANSArchives of internal medicine (1960), 1909
- A STUDY OF THE PATHOLOGICAL ANATOMY OF THE PANCREAS IN NINETY CASES OF DIABETES MELLITUSThe Journal of Experimental Medicine, 1909