A FLUORIMETRIC ASSAY FOR MINUTE AMOUNTS OF SOME THIOHYDANTOINS

Abstract
A fluorimetric assay sensitive to μg. quantities of certain thiohydantoins has been devised using dichloroquinone chloroimide as a fluorescence reagent. The nature of the buffer used is critical. Satisfactory results have been obtained for recoveries from urine, spinal fluid and plasma. 16 thiohydantoins and some related compounds have been examined by the suggested technique.