GRAFT-VERSUS-HOST REACTION
- 1 July 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Transplantation
- Vol. 24 (1) , 74-77
- https://doi.org/10.1097/00007890-197707000-00011
Abstract
In two H-2b anti-H-2d but not in H-2b anti-H-2k donor-recipient combinations, graft-versus-host reaction (GVHR) mortality was found to vary as a function of the host's genetic background; the same non-major histocompatibility complex genes and/or antigens which influence GVHR mortality do not influence the intensity of GVHR splenomegaly or the time of skin rejection. In contrast, the severity of GVHR mortality correlates with the intensity of stimulation in mixed lymphocyte culture. The roles of minor histocompatibility (H) antigens and Mis product are discussed.This publication has 0 references indexed in Scilit: