Protection Against Rh D‐Haemolytic Disease of the Newborn by a Diminished Transport of Maternal IgG to the Fetus
- 1 June 1993
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 65 (1) , 59-61
- https://doi.org/10.1111/j.1423-0410.1993.tb04526.x
Abstract
IgG present in the circulation of newborn infants is predominantly of maternal origin. In cases of severe Rh D alloimmunization, the maternal anti-D antibodies may lead to Rh D-haemolytic disease of the newborn. However, an impaired placental transport of maternal IgG could be associated with the protection of the fetus/newborn against haemolytic disease as shown in this case report.Keywords
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