Isolation of Translactone-containing Triterpenes with Thrombin Inhibitory Activities from the Leaves of Lantana camara
- 19 September 1998
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 61 (11) , 1328-1331
- https://doi.org/10.1021/np970464j
Abstract
Methanolic extracts prepared from the leaves of Lantana camara have been found to inhibit human thrombin. An assay, in which thrombin activity is measured as a function of clot formation from fibrinogen, was used to guide the fractionation and purification of five principal active constituents (1−5), which were all characterized as 5,5-trans-fused cyclic lactone-containing euphane triterpenes.Keywords
This publication has 1 reference indexed in Scilit:
- Verbascoside Isolated from Lantana camara, an Inhibitor of Protein Kinase CJournal of Natural Products, 1991