A developmentally regulated disappearance of slow myosin in fast‐type muscles of the mouse
- 5 November 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 177 (1) , 51-56
- https://doi.org/10.1016/0014-5793(84)80979-5
Abstract
Histochemistry and immunocytochemistry using an antibody to adult rat slow-type myosin demonstrated that about 10% of the fibers in the mouse extensor digitorum longus and semimembranosus muscles contain slow myosin during the first month after birth. In adult animals, these muscles have only 0-08% slow myosin-containing fibers. These results demonstrate a developmentally linked disappearance of an adult-type myosin, and show that the adult phenotype of muscle fibers is not necessarily determined before birth as previously suggested.Keywords
This publication has 30 references indexed in Scilit:
- Fibre type composition of single motor units during synapse elimination in neonatal rat soleus muscleNature, 1984
- Myosin isozyme transitions occurring during the postnatal development of the rat soleus muscleDevelopmental Biology, 1984
- Monoclonal antibodies localize changes on myosin heavy chain isozymes during avian myogenesisCell, 1983
- Coordinate expression of alkali and DTNB myosin light chains during transformation of rabbit fast muscle by chronic stimulationFEBS Letters, 1983
- Changes of activity patterns in slow and fast muscles during postnatal developmentDevelopmental Brain Research, 1983
- Developmental appearance of myosin heavy and light chain isoforms in vivo and in vitro in chicken skeletal muscleDevelopmental Biology, 1982
- Fiber type susceptibility in the dystrophic mouseExperimental Neurology, 1981
- Three myosin heavy-chain isozymes appear sequentially in rat muscle developmentNature, 1981
- Development of muscle fiber specialization in the rat hindlimb.The Journal of cell biology, 1981
- Rabbit skeletal myosin isoenzymes from fetal, fast-twitch and slow-twitch musclesNature, 1979