Abstract
The object of this study was to observe the relation between population density and adrenocortical activity, as measured by adrenal weights and blood eosinophil levels, in free-living populations of the meadow vole, Microtus pennsylvanicus. The study was initiated to test the hypothesis presented by Christian (1950) that high population density constitutes a stress factor eliciting a response from the adrenopituitary systems of individuals making up the population and thus brings about the occurrence of the General Adaptation Syndrome of Selye (1946).

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