Activity of eight aminoglycosides against isolates of Serratia marcescens from four hospitals
- 1 January 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 4 (1) , 47-55
- https://doi.org/10.1093/jac/4.1.47
Abstract
The susceptibility to 8 aminoglycosides of 146 clinical isolates of Serratia marcescens from 4 different hospitals, has been determined. Most isolates were multiply resistant: namely 62% to carbenicillin, 79% to kanamycin, 59% to streptomycin, 56% to gentamicin and sisomicin, and 5% to tobramycin. All strains were susceptible to amikacin and netilmicin. The predominant profile of resistance to aminoglycosides was simultaneous resistance to streptomicin-kanamycin-paromomycin and sisomicin. Transfer experiments confirmed that the resistance to these drugs was plasmid-mediated.Keywords
This publication has 1 reference indexed in Scilit:
- An Outbreak of Nosocomial Infection Due to Multiply Resistant Serratia marcescens: Evidence of Interhospital SpreadThe Journal of Infectious Diseases, 1976