Ischemic Stroke Injury Is Reduced in Mice Lacking a Functional NADPH Oxidase
- 1 November 1997
- journal article
- research article
- Published by Wolters Kluwer Health in Stroke
- Vol. 28 (11) , 2252-2258
- https://doi.org/10.1161/01.str.28.11.2252
Abstract
Background and Purpose Free radicals account for a significant proportion of the brain damage that occurs during ischemic stroke. Using mutant mice (X-CGD) with a dysfunctional phagocytic NADPH oxi...Keywords
This publication has 26 references indexed in Scilit:
- Tissue Plasminogen Activator for Acute Ischemic StrokeNew England Journal of Medicine, 1995
- Role of Neutrophils in Radical Production during Ischemia and Reperfusion of the Rat Brain: Effect of Neutrophil Depletion on Extracellular Ascorbyl Radical FormationJournal of Cerebral Blood Flow & Metabolism, 1995
- Cytochrome b-558 α-subunit cloning and expression in rat aortic smooth muscle cellsBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1995
- Nitric oxide and oxygen radicals: a question of balanceFEBS Letters, 1995
- The functional expression of p47‐phox and p67‐phox may contribute to the generation of superoxide by an NADPH oxidase‐like system in human fibroblastsFEBS Letters, 1994
- Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemiaNeuroReport, 1993
- Chronic Granulomatous Disease: The Solving of a Clinical Riddle at the Molecular LevelClinical Immunology and Immunopathology, 1993
- Tissue Destruction by NeutrophilsNew England Journal of Medicine, 1989
- Central nervous system trauma and strokeII. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidationFree Radical Biology & Medicine, 1989
- Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.Journal of Clinical Investigation, 1988