Translocation 9q/13q resulting in duplication (trisomy 9pter→9q22) and deficiency (monosomy 13pter→13q12)

Abstract
A profoundly retarded, 12‐year‐old female is described. Her phenotype is compatible with the clinical features of the trisomy 9p syndrome. Cytogenetic analyses showed her to be trisomic for 9pter→9q22 and monosomic for 13pter→13q12, as the result of adjacent‐2 segregation during meiosis in her mother. The family pedigree shows this (9;13) translocation to be present in at least three generations.